HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54677605, compound → HCID 54677480, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54677605 | HCID 54677605 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 54677480 | HCID 54677480 | — |
Reaction Steps
Benzyl-(2S,4R)-2-(4-{[(4-fluorobenzyl)amino]carbonyl}-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)-4-methoxypyrrolidine-1-carboxylate was dissolved in methanol and Pd/C 10% wt (14% w/w) was added. The mixture was stirred under H2 atmosphere at room temperature. After 2 hours the reaction mixture was filtered and methanol was removed in vacuo to give title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820660B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-d6f17db630f04a088eada93b70b1682f |
| Source note | uspto-grants-2010_10 |