HCID 21864857, compound → HCID 66894206, compound

HRID 1161992Notes

Reaction equation

HRID 1161992 reaction equation
[CH2:1]([N:3]([CH2:25][CH3:26])[C:4](=[O:24])[CH2:5][N:6]1[CH2:11][CH2:10][N:9]([C:12]2[C:20]3[O:19][CH:18]=[CH:17][C:16]=3[CH:15]=[C:14]([N+:21]([O-])=O)[CH:13]=2)[CH2:8][CH2:7]1)[CH3:2].NC1C=C(N2CCN(C(OC(C)(C)C)=O)CC2)C2OC=CC=2C=1>>[NH2:21][C:14]1[CH:13]=[C:12]([N:9]2[CH2:10][CH2:11][N:6]([CH2:5][C:4]([N:3]([CH2:25][CH3:26])[CH2:1][CH3:2])=[O:24])[CH2:7][CH2:8]2)[C:20]2[O:19][CH:18]=[CH:17][C:16]=2[CH:15]=1

Participants

3

Reactant 2

HCID 21864857HCID 21864857, compoundHCID 66891841HCID 66891841, compound2×

Product 1

HCID 66894206HCID 66894206, compound

Procedure

Reduction of the nitro group in N,N-diethyl-2-[4-(5-nitro-1-benzofuran-7-yl)piperazin-1-yl]acetamide (0.3 g, 0.83 mmol; Intermediate 22) was performed according to the procedure of Intermediate 10. Yield: 0.19 g (70%). This material was used in the next step without further purification. MS (ESI+) m/z 331.2 (M+H)+.

Workup

  1. customThis material was used in the next step without further purification

Sources & evidence

ORD record
ord-211ed25683a3458b9f750fa4f28a6ced
Source dataset
uspto-grants-2010_10
Patent number
US07820675B2

Reaction notes

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