5-(5-Nitro-benzofuran-7-yl)-pyridin-2-ylamine → 5-(5-Amino-1-benzofuran-7-yl)pyridin-2-amine

HRID 1162015Notes

Reaction equation

HRID 1162015 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C:13]2[CH:14]=[CH:15][C:16]([NH2:19])=[N:17][CH:18]=2)[C:7]2[O:11][CH:10]=[CH:9][C:8]=2[CH:12]=1)([O-])=O.N1(CCNC2C3OC=CC=3C=C(N)C=2)CCOCC1>>[NH2:1][C:4]1[CH:5]=[C:6]([C:13]2[CH:14]=[CH:15][C:16]([NH2:19])=[N:17][CH:18]=2)[C:7]2[O:11][CH:10]=[CH:9][C:8]=2[CH:12]=1

Participants

3

Reactant 2

HCID 668922105-(5-Nitro-benzofuran-7-yl)-pyridin-2-ylamine2×HCID 86058078N7-(2-Morpholin-4-ylethyl)-1-benzofuran-5,7-diamine

Product 1

HCID 668919545-(5-Amino-1-benzofuran-7-yl)pyridin-2-amine

Procedure

The title compound was prepared from 5-(5-nitro-benzofuran-7-yl)-pyridin-2-ylamine (Intermediate 39) according to the procedure of Intermediate 28. The product was used directly in the subsequent reaction.

Workup

  1. customThe product was used directly in the subsequent reaction

Sources & evidence

ORD record
ord-4279f1efc3e244cfb626bea9d318ac03
Source dataset
uspto-grants-2010_10
Patent number
US07820675B2

Reaction notes

Loading…