HCID 66893726, compound → HCID 66893956, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described for Example 84 starting from tert-butyl trans-4-[(5-amino-1-benzofuran-7-yl)oxy]-3-fluoropiperidine-1-carboxylate (Intermediate 53) and 3,6-dichloro-2-methylbenzenesulfonyl chloride. Yield: 39 mg (19%), HPLC purity=98%, m/z=473 (M+H)+, 1H NMR (270 MHz, methanol-d4) δ ppm 2.11-2.34 (m, 2H) 2.47-2.54 (m, 3H) 3.14-3.56 (m, 3H) 3.63-3.79 (m, 1H) 4.76-4.97 (m, 1H) 4.97-5.22 (m, 1H) 6.77 (d, J=1.98 Hz, 1H) 6.83 (d, J=1.73 Hz, 1H) 7.06 (d, J=1.98 Hz, 1H) 7.26 (d, J=1.98 Hz, 1H) 7.50 (d, J=1.98 Hz, 1H) 7.74 (d, J=2.23 Hz, 1H).

Provenance & Evidence