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HRID1162068

反应详情

EQUATION

反应方程式

HRID 1162068 的结构方程式

REACTANTS

反应物

2
结构：O=S(=O)(Cl)c1ccccc1Cl
HCID76187

Benzenesulfonyl chloride, 2-chloro-

C6H4Cl2O2S

结构：C[C@@H]1CN(C(=O)OC(C)(C)C)[C@@H](C)CN1Cc1cc(N)cc2ccoc12
HCID66892496

tert-Butyl trans-4-[(5-amino-1-benzofuran-7-yl)methyl]-2,5-dimethylpiperazine-1-carboxylate

C20H29N3O3

PRODUCTS

生成物

1
结构：C[C@@H]1CN(C(=O)OC(C)(C)C)[C@@H](C)CN1Cc1cc(NS(=O)(=O)c2ccccc2Cl)cc2ccoc12
HCID66893650

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC#N
溶剂HCID6342

Acetonitrile

C2H3N

2 次

PROCEDURE

实验过程

The title product was prepared according to the procedure of Example 121, Step 4, starting from tert-butyl trans-4-[(5-amino-1-benzofuran-7-yl)methyl]-2,5-dimethylpiperazine-1-carboxylate (obtained in Example 121, Step 3) and 2-chlorobenzenesulfonyl chloride (0.043 g, 0.2 mmol). Yield: 0.017 g (26%). HPLC 94% RT=2.01 min (System A; 10-97% MeCN over 3 min), 98% RT=1.85 min (System B; 10-97% MeCN over 3 min). MS (ESI+) m/z 534.2 (M+H)+.