HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-1-propanol → HCID 57470621, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-1-propanol | HCID 9086 | — |
| Reactant | 3-Bromo-6-chloroimidazo(1,2-b)pyridazine | HCID 12872323 | — |
| Reactant | Dichloromethane methanol ammonium hydroxide | HCID 21896990 | — |
| Product | HCID 57470621 | HCID 57470621 | — |
Reaction Steps
Prepared from 3-bromo-6-chloroimidazo[1,2-b]pyridazine and 3-amino-1-propanol according to general procedure 1 providing the amino compound (493 mg, 84%) as a yellow solid: Rf=0.56 (CH2Cl2/MeOH/NH4OH, 160:18:2); 1H NMR (500 MHz, CD3OD) δ 7.56 (d, J=9.7 Hz, 1H), 7.41 (s, 1H), 6.71 (d, J=9.7 Hz, 1H), 3.71 (t, J=6.3 Hz, 2H), 3.50 (t, J=6.8 Hz, 2H), 1.93 (quin, J=6.6 Hz, 2H); ES-MS: (M+H)=271, 273 m/z.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820670B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-8970eabf2750437da2d82669ac9a848d |
| Source note | uspto-grants-2010_10 |