HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-1-butanol → HCID 57470629, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-1-butanol | HCID 25868 | — |
| Reactant | 3-Bromo-6-chloroimidazo(1,2-b)pyridazine | HCID 12872323 | — |
| Reactant | Dichloromethane methanol ammonium hydroxide | HCID 21896990 | — |
| Product | HCID 57470629 | HCID 57470629 | — |
Reaction Steps
Prepared from 3-bromo-6-chloroimidazo[1,2-b]pyridazine and 4-aminobutan-1-ol according to general procedure 1 providing the intermediate (150 mg, 82%) as a yellow solid: Rf=0.45 (CH2Cl2/MeOH/NH4OH, 160:18:2); 1H NMR (500 MHz, CD3OD) δ 7.53 (d, J=9.7 Hz, 1H), 7.38 (s, 1H), 6.68 (d, J=9.7 Hz, 1H), 3.62 (t, J=6.6 Hz, 2H), 3.40 (t, J=6.9 Hz, 2H), 1.77-1.72 (m, 2H), 1.69-1.64 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820670B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-5e88c2aa03d646f5a7b7a9633f8203cc |
| Source note | uspto-grants-2010_10 |