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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1162414Generated: October 29, 2026

HCID 66995417, compound → HCID 136368380, compound

https://huagongshe.com/reaction/1162414

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66995417HCID 66995417—
CatalystHCID 178418390HCID 178418390—
SolventMeOH tetrahydrofuranHCID 21899815—
ProductHCID 136368380HCID 136368380—

Reaction Steps

Methyl 2-(3-cyano-4-benzyloxy-5-fluorophenyl)isonicotinate is stirred at room temperature in methanol-THF (1:1) under a hydrogen atmosphere at normal pressure in the presence of palladium-carbon to obtain methyl 2-(3-cyano-5-fluoro-4-hydroxyphenyl)isonicotinate. FN: 271.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07820700B2
Source datasetuspto-grants-2010_10
ORD IDord-adb2b66cc0e149a3b40867dfeb81b3e8
Source noteuspto-grants-2010_10