4-Isopropylacetophenone → 2-Bromo-1-(4-(propan-2-yl)phenyl)ethan-1-one

HRID 1162537Notes

Reaction equation

HRID 1162537 reaction equation
[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10](=[O:12])[CH3:11])=[CH:6][CH:5]=1)([CH3:3])[CH3:2].C1CNC(=O)C1.[Br:19][Br-]Br>>[Br:19][CH2:11][C:10]([C:7]1[CH:8]=[CH:9][C:4]([CH:1]([CH3:3])[CH3:2])=[CH:5][CH:6]=1)=[O:12]

Participants

2

Reactant 1

HCID 125784-Isopropylacetophenone

Product 1

HCID 140427562-Bromo-1-(4-(propan-2-yl)phenyl)ethan-1-one

Procedure

2-Bromo-1-(4-isopropyl-phenyl)-ethanone was prepared (0.95 g) following general procedure A using 1-(4-isopropyl-phenyl)-ethanone (0.66 mL, 3.92 mmol) and pyrrolidone hydrotribromide (2.1 g, 4.31 mmol).

Sources & evidence

ORD record
ord-9616829654a848da94744fa08df700c3
Source dataset
uspto-grants-2010_10
Patent number
US07820704B2

Reaction notes

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