HCID 24730368, compound → HCID 68647641, compound

HRID 1162543Notes

Reaction equation

HRID 1162543 reaction equation
[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[N:11]=[C:12]([NH:15][CH2:16][C:17]3[S:18][CH:19]=[CH:20][CH:21]=3)[S:13][CH:14]=2)=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[C:22]([O:26][C:27](=[O:33])[CH2:28][S:29](Cl)(=[O:31])=[O:30])([CH3:25])([CH3:24])[CH3:23]>>[C:22]([O:26][C:27](=[O:33])[CH2:28][S:29](=[O:30])(=[O:31])[N:15]([C:12]1[S:13][CH:14]=[C:10]([C:7]2[CH:6]=[CH:5][C:4]([CH:1]([CH3:3])[CH3:2])=[CH:9][CH:8]=2)[N:11]=1)[CH2:16][C:17]1[S:18][CH:19]=[CH:20][CH:21]=1)([CH3:25])([CH3:23])[CH3:24]

Participants

3

Reactant 2

HCID 24730368HCID 24730368, compoundHCID 43350783Tert-butyl 2-(chlorosulfonyl)acetate

Product 1

HCID 68647641HCID 68647641, compound

Procedure

[4-(4-Isopropyl-phenyl)-thiazol-2-yl]-thiophen-2-ylmethyl-amine, chlorosulfonyl-acetic acid tert-butyl ester were combined according to general procedure C (method 2) to provide {[4-(4-isopropyl-phenyl)-thiazol-2-yl]-thiophen-2-ylmethyl-sulfamoyl}-acetic acid tert-butyl ester. LCMS m/z: 494 (M+1)+.

Sources & evidence

ORD record
ord-9e04f94d3a454a2fb1f5b145bdac755c
Source dataset
uspto-grants-2010_10
Patent number
US07820704B2

Reaction notes

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