HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → {[4-(4-Isopropyl-phenyl)-thiazol-2-yl]-thiophen-2-ylmethyl-sulfamoyl}-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | {[4-(4-Isopropyl-phenyl)-thiazol-2-yl]-thiophen-2-ylmethyl-sulfamoyl}-acetic acid tert-butyl ester | HCID 68647641 | — |
| Product | {[4-(4-Isopropyl-phenyl)-thiazol-2-yl]-thiophen-2-ylmethyl-sulfamoyl}-acetic acid | HCID 59520347 | — |
Reaction Steps
The above ester was treated with 4M HCl as outlined in general procedure G1 to provide {[4-(4-Isopropyl-phenyl)-thiazol-2-yl]-thiophen-2-ylmethyl-sulfamoyl}-acetic acid. LCMS m/z: 438 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820704B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-8e8ebdbd7a044317bc611066d2c81548 |
| Source note | uspto-grants-2010_10 |