HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentylthiourea → Cyclopentyl-[4-(4-isopropyl-phenyl)-thiazol-2-yl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentylthiourea | HCID 736945 | — |
| Reactant | 2-Bromo-1-(4-(propan-2-yl)phenyl)ethan-1-one | HCID 14042756 | — |
| Product | Cyclopentyl-[4-(4-isopropyl-phenyl)-thiazol-2-yl]-amine | HCID 86079884 | — |
Reaction Steps
Cyclopentyl-[4-(4-isopropyl-phenyl)-thiazol-2-yl]-amine was prepared following procedure B using cyclopentyl-thiourea (1.6 g, 10.7 mmol) and 2-bromo-1-(4-isopropyl-phenyl)-ethanone (2.6 g, 10.7 mmol). Purification (Silica gel, ethyl acetate/hexane 5:95) provided the product (2.9 g). LCMS m/z: 287 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820704B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-97c1b89297b540d5896490f64fbc0b88 |
| Source note | uspto-grants-2010_10 |