HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonamide → HCID 59520315, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonamide | HCID 7370 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | HCID 11668171 | HCID 11668171 | — |
| Solvent | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Product | HCID 59520315 | HCID 59520315 | — |
Reaction Steps
N-(3-{[4-(4-isopropyl-phenyl)-thiazol-2-yl]-thiophen-2-ylmethyl-amino}-propionyl)-benzenesulfonamide was prepared following procedure K using 3-{[4-(4-isopropyl-phenyl)-thiazol-2-yl]-thiophen-2-ylmethyl-amino}-propionic acid (Prepared in Example 35) (50 mg, 0.125 mmol), CDI (62 mg, 0.39 mmol), DBU (30 μl, 0.2. mmol), and benzene sulfonamide (41 mg, 0.26 mmol). Purification (Silica gel, ethyl acetate/hexane 1:4) provided the product (10 mg). LCMS m/z: 527 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820704B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-50ee126a3d9240fda63887b1abd42fd7 |
| Source note | uspto-grants-2010_10 |