1-(4-Amino-3-fluorophenyl)pyridin-2-one → HCID 58748294, compound

Participants

Reaction Steps

8.2 Using general procedure F [(R)-3-(5-chloro-thiophene-2-sulfonylamino)-pyrrolidin-1-yl]-acetic acid ethyl ester was reacted with 1-(4-amino-3-fluoro-phenyl)-1H-pyridin-2-one (CAS 536747-52-1, prepared according to WO 2003045912) to give 2-[(R)-3-(5-chloro-thiophene-2-sulfonylamino)-pyrrolidin-1-yl]-N-[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-acetamide. White solid. MS 511.3 ([M+H]+)

Provenance & Evidence