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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1162623Generated: October 29, 2026

Ethanolamine → HCID 58748184, compound

https://huagongshe.com/reaction/1162623

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolamineHCID 700—
ReactantHCID 58748169HCID 58748169—
ProductHCID 58748184HCID 58748184—

Reaction Steps

Using general procedure D (2S,4R)-4-[(5-chloro-thiophene-2-carbonyl)-amino]—1-{[2-fluoro-4-(2-oxo-pyridin-1-yl)-phenylcarbamoyl]-methyl}-pyrrolidine-2-carboxylic acid (example 12) was coupled with 2-aminoethanol to give (2S,4R)-4-[(5-chloro-thiophene-2-carbonyl)-amino]-1-{[2-fluoro-4-(2-oxo-pyridin-1-yl)-phenylcarbamoyl]-methyl}-pyrrolidine-2-carboxylic acid (2-hydroxy-ethyl)-amide. White solid. MS 562.5 ([M+H]+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07820699B2
Source datasetuspto-grants-2010_10
ORD IDord-ab4ba4bf9ad74f08a14fe9fcab10b35b
Source noteuspto-grants-2010_10