Methylamine hydrochloride → HCID 58748339, compound

Participants

Role	Name	HCID	Charge
Reactant	Methylamine hydrochloride	HCID 6364545	—
Reactant	HCID 58748169	HCID 58748169	—
Product	HCID 58748339	HCID 58748339	—

Reaction Steps

Using general procedure D (2S,4R)-4-[(5-chloro-thiophene-2-carbonyl)-amino]-1-{[2-fluoro-4-(2-oxo-pyridin-1-yl)-phenylcarbamoyl]-methyl}-pyrrolidine-2-carboxylic acid (example 12) was coupled with methylamine hydrochloride to give (2S,4R)-4-[(5-chloro-thiophene-2-carbonyl)-amino]-1-{[2-fluoro-4-(2-oxo-pyridin-1-yl)-phenylcarbamoyl]-methyl}-pyrrolidine-2-carboxylic acid methylamide. White solid. MS 532.3 ([M+H]+)

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07820699B2
Source dataset	uspto-grants-2010_10
ORD ID	ord-e663dbc660fd49d782df58efa76780a9
Source note	uspto-grants-2010_10