HCID 58748239, compound → HCID 42643389, compound

Participants

Reaction Steps

17.5 Using general procedure A 5-chloro-thiophene-2-carboxylic acid ((3R,5S)-5-pyrrolidin-1-ylmethyl-pyrrolidin-3-yl)-amide was reacted with 2-bromo-[2-fluoro-4-(2-oxo-pyridin-1-yl)-phenyl]-acetamide (example 11.3) to give 5-chloro-thiophene-2-carboxylic acid ((3R,5S)-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-5-pyrrolidin-1-ylmethyl-pyrrolidin-3-yl)-amide. Light yellow solid. MS 558.2 ([M+H]+)

Provenance & Evidence