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HRID1162655

反应详情

EQUATION

反应方程式

HRID 1162655 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1ccc(Cl)s1
HCID95048

2-Thiophenecarboxylic acid, 5-chloro-

C5H3ClO2S

结构：CC(C)(C)OC(=O)N1CC[C@H](CN)C1
HCID1515152

tert-Butyl (3R)-3-(aminomethyl)pyrrolidine-1-carboxylate

C10H20N2O2

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CC[C@H](CNC(=O)c2ccc(Cl)s2)C1
HCID58748286

未命名化合物

PROCEDURE

实验过程

50.1 Using general procedure E, (R)-3-aminomethyl-1-N-tert-butoxycarbonyl-pyrrolidine was coupled with 5-chlorothiophene-2-carboxylic acid to give (R)-3-{[(5-chloro-thiophene-2-carbonyl)-amino]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester. Brown oil. MS 345.0 ([M+H]+)