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HRID1162662

反应详情

EQUATION

反应方程式

HRID 1162662 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1cc(Br)c(Br)s1
HCID80611

4,5-Dibromothenoic acid

C5H2Br2O2S

结构：CC(C)(C)OC(=O)N1CC[C@H](CN)C1
HCID1515152

tert-Butyl (3R)-3-(aminomethyl)pyrrolidine-1-carboxylate

C10H20N2O2

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CC[C@H](CNC(=O)c2cc(Br)c(Br)s2)C1
HCID58748268

未命名化合物

PROCEDURE

实验过程

58.1 Using general procedure E, (R)-3-aminomethyl-1-N-tert-butoxycarbonyl-pyrrolidine was coupled with 4,5-dibromothiophene-2-carboxylic acid to give (R)-3-{[(4,5-dibromo-thiophene-2-carbonyl)-amino]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester. White solid. MS 466.9 ([M−H]−)