HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl (3R)-3-(aminomethyl)pyrrolidine-1-carboxylate → HCID 58748165, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl (3R)-3-(aminomethyl)pyrrolidine-1-carboxylate | HCID 1515152 | — |
| Reactant | 6-Chloro-1-benzothiophene-2-carboxylic acid | HCID 7141919 | — |
| Product | HCID 58748165 | HCID 58748165 | — |
Reaction Steps
65.1 Using general procedure E, (R)-3-aminomethyl-1-N-tert-butoxycarbonyl-pyrrolidine was coupled with 6-chloro-benzo[b]thiophene-2-carboxylic acid (prepared according to WO 2001007436) to give (R)-3-{[(6-chloro-benzo[b]thiophene-2-carbonyl)-amino]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester. White solid. MS 392.9 ([M−H]−)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820699B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-d6c45107f64d48dcb2b46cf3a9247095 |
| Source note | uspto-grants-2010_10 |