HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrophenyl chloroformate → [2-Fluoro-4-(3-oxo-morpholin-4-yl)-phenyl]-carbamic acid 4-nitro-phenyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrophenyl chloroformate | HCID 82129 | — |
| Reactant | 4-(4-Amino-3-fluorophenyl)morpholin-3-one | HCID 53417798 | — |
| Product | [2-Fluoro-4-(3-oxo-morpholin-4-yl)-phenyl]-carbamic acid 4-nitro-phenyl ester | HCID 58748330 | — |
Reaction Steps
72.1 Using general method G, 4-(4-amino-3-fluoro-phenyl)-morpholin-3-one (prepared according to WO 2003045912) was activated with 4-nitrophenyl chloroformate to give [2-fluoro-4-(3-oxo-morpholin-4-yl)-phenyl]-carbamic acid 4-nitro-phenyl ester. White solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820699B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-428909bde0bd4b4eb206f489391c8a1d |
| Source note | uspto-grants-2010_10 |