HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-2-thiophenecarboxylic acid → HCID 58748269, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-2-thiophenecarboxylic acid | HCID 95048 | — |
| Reactant | (+-)-2-(Aminomethyl)-1-N-Boc-pyrrolidine | HCID 2756484 | — |
| Product | HCID 58748269 | HCID 58748269 | — |
Reaction Steps
75.1 Using general procedure E, rac-2-aminomethyl-1-N-tert-butoxycarbonyl-pyrrolidine was coupled with 5-chlorothiophene-2-carboxylic acid to give rac-2-{[(5-chloro-thiophene-2-carbonyl)-amino]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester. Brown oil. MS 345.0 ([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820699B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-ad36fbaba5ea4936b15f424bc6c22a5a |
| Source note | uspto-grants-2010_10 |