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HRID1162698

反应详情

EQUATION

反应方程式

HRID 1162698 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1ccc(Cl)s1
HCID95048

2-Thiophenecarboxylic acid, 5-chloro-

C5H3ClO2S

结构：CC(=O)O.CC(=O)O[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1CN
HCID68646955

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)O[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1CNC(=O)c1ccc(Cl)s1
HCID58748221

未命名化合物

PROCEDURE

实验过程

79.4 Using general procedure E, (3S,4R)-3-acetoxy-4-aminomethyl-pyrrolidine-1-carboxylic acid tert-butyl ester acetate was coupled with 5-chlorothiophene-2-carboxylic acid to give (3S,4R)-3-acetoxy-4-{[(5-chloro-thiophene-2-carbonyl)-amino]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester. Brown oil. MS 347.0 ([M-iso-butene+H]+)