HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-2-thiophenecarboxylic acid → HCID 58748164, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-2-thiophenecarboxylic acid | HCID 95048 | — |
| Reactant | HCID 68647310 | HCID 68647310 | — |
| Product | HCID 58748164 | HCID 58748164 | — |
Reaction Steps
80.4 Using general procedure E, (3R,4S)-3-aminomethyl-4-methoxy-pyrrolidine-1-carboxylic acid tert-butyl ester acetate was coupled with 5-chlorothiophene-2-carboxylic acid to give (3R,4S)-3-{[(5-chloro-thiophene-2-carbonyl)-amino]-methyl}-4-methoxy-pyrrolidine-1-carboxylic acid tert-butyl ester. Colorless foam. MS 318.9 ([M−isobutene+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820699B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-2b4aace7c93145f7912f0bff6d1694e0 |
| Source note | uspto-grants-2010_10 |