Cyclopropylamine → HCID 58748292, compound

Participants

Reaction Steps

According to general procedure D ((3S,4S)-4-[(5-chloro-thiophene-2-carbonyl)-amino]-1-{[2-fluoro-4-(2-oxo-pyridin-1-yl)-phenylcarbamoyl]-methyl}-pyrrolidin-3-yloxy)-acetic acid (example 97) was reacted with cyclopropylamine to give 5-chloro-thiophene-2-carboxylic acid ((3S,4S)-4-cyclopropylcarbamoylmethoxy-1-{[2-fluoro-4-(2-oxo-pyridin-1-yl)-phenylcarbamoyl]-methyl}-pyrrolidin-3-yl)-amide. White solid. MS588.5 ([M+H]+)

Provenance & Evidence