Acetic Anhydride → HCID 178475360, compound

Participants

Reaction Steps

4,6-Dihydroxy-quinazoline-2-carboxylic acid amide (12 mmol) are dissolved in warm D (20 ml) and triethylamine (13.2 mmol) is added to the stirred mixture. After cooling to RT a solution of acetic acid anhydride in DMF (10 ml) is added dropwise and the mixture is stirred overnight. The solvent is removed and the solid material formed is suspended in ethanol and the solid filtered of and dried (vacuum). A powder with mp. 250° C. is obtained.

Provenance & Evidence