(3S)-(-)-3-(Dimethylamino)pyrrolidine → (3S)-N,N-dimethyl-1-{4-[(1-methyl-1H-indol-3-yl)methyl]benzoyl}pyrrolidin-3-amine

Participants

Reaction Steps

Using essentially the same procedure described in Example 228 and employing methyl 4-((1-methyl-1H-indol-3-yl)methyl)benzoate and (S)—N,N-dimethylpyrrolidin-3-amine as starting materials, the title compound is obtained as a white solid, mp 101-105° C., identified by H1 NMR and mass spectral analyses. MS (ES) m/z 362.2; MS (ES) m/z 723.4.

Provenance & Evidence