反应详情

Ethyl 8-(benzyloxy)-2,3-dihydro-1-benzoxepine-4-carboxylate (3.5 g) was dissolved in ethanol (50 mL), and the solution was subjected to catalytic reduction using 10% palladium on carbon (0.35 g) for 3 days. The catalyst was filtered off, and the solvent of the filtrate was evaporated. The residue was purified by silica gel column chromatography (ethyl acetate:hexane) to give the title compound (2.7 g) as an oil.

1. customfor 3 days
2. filtrationThe catalyst was filtered off
3. customthe solvent of the filtrate was evaporated
4. customThe residue was purified by silica gel column chromatography (ethyl acetate:hexane)