Sodium sulfate decahydrate → HCID 23111775, compound

Participants

Reaction Steps

To a solution of 3-(1-benzothien-3-yl)benzaldehyde (2.1 g, 8.81 mmol) in anhydrous tetrahydrofuran (30 mL) was added lithium aluminum hydride (0.37 g, 9.75 mmol) under ice-cooling, and the mixture was stirred at room temperature for 2 hr. The reaction solution was ice-cooled, and sodium sulfate decahydrate (3.0 g, 5.74 mmol) was added, and the mixture was stirred at room temperature for 1 hr. The precipitated insoluble material was filtered through celite, and the filtrate was concentrated under reduced pressure. The obtained residue was subjected to silica gel column chromatography (ethyl acetate:hexane=1:5-1:3) to give the title compound (2.0 g, yield 95%) as a colorless oil.

Provenance & Evidence