Sodium sulfate decahydrate → 2-[(3-Phenoxybenzyl)thio]-4,5,6,7-tetrahydro-1,3-benzothiazol-7-ol

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Reaction Steps

To a solution of 2-[(3-phenoxybenzyl)thio]-5,6-dihydro-1,3-benzothiazol-7(4H)-one (2.50 g, 6.80 mmol) in tetrahydrofuran (50 mL) was added by portions lithium aluminum hydride (280 mg) under ice-cooling, and the mixture was stirred at the same temperature for 1 hr. Sodium sulfate decahydrate (1.5 g) was added to reaction mixture, and the mixture was stirred at room temperature for 1 hr. The insoluble material was filtered off, and the filtrate was concentrated under reduced pressure to give the title compound (2.20 g, yield 87%) as a colorless oil.

Provenance & Evidence