HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1163333Generated: October 26, 2026
HCID 13606905, compound → N-(2,4-difluorophenyl)-6-fluoro-7-chloro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid
https://huagongshe.com/reaction/1163333
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 13606905 | HCID 13606905 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | N-(2,4-difluorophenyl)-6-fluoro-7-chloro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid | HCID 11484989 | — |
Reaction Steps
A mixture of 2.0 g of 7-chloro-1-(2,4-difluoro-phenyl)-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester (5.23 mmol) in 16 ml acetic acid and 16 ml HCl 37% was stirred 25 hrs at 90° C., and evaporated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07820823B2 |
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| Source dataset | uspto-grants-2010_10 |
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| ORD ID | ord-f1bf6c2ef9c54c83b2c6dc4497d2b665 |
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| Source note | uspto-grants-2010_10 |
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