Ethylamine → HCID 67274438, compound

HRID 1163336Notes

Reaction equation

HRID 1163336 reaction equation
[C:1]1([CH2:7][N:8]2[CH2:13][CH2:12][N:11]([CH2:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH2:10][CH:9]2[CH:21]=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:23]([NH2:25])[CH3:24]>ClCCl>[CH2:7]([N:8]1[CH2:13][CH2:12][N:11]([CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:10][CH:9]1[CH:21]=[N:25][CH2:23][CH3:24])[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 6341EthylamineHCID 154809991,4-Dibenzylpiperazine-2-carbaldehyde

Product 1

HCID 67274438HCID 67274438, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 0.5 g (1,4-bis(phenylmethyl)-2-piperazin-carboxaldehyd in 5 ml of dichloromethane was added 0.54 ml ethylamine and 0.5 g molecular sieves. The reaction mixture was stirred for 30 min at rt then filtered. The filtrate was evaporated to dryness.

Workup

  1. filtrationthen filtered
  2. customThe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-1871d8010f5e496384cb4e83ed620633
Source dataset
uspto-grants-2010_10
Patent number
US07820823B2

Reaction notes

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