HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 67274376, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | HCID 86597767 | HCID 86597767 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67274376 | HCID 67274376 | — |
Reaction Steps
A solution of 2.51 g (5.35 mmol) 4-[4-{(5R)-5-azidomethyl2-oxo-oxazolidin-3-yl}-2-fluoro-phenylamino]-piperidine-1-carboxylic acid benzyl ester, 1.54 g (5.88 mmol) triphenylphosphine and 964 μl (53.5 mmol) water in 30 ml THF was stirred at 50° C. for 16 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820823B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-fdf72b58b1364495a4a763883927030d |
| Source note | uspto-grants-2010_10 |