HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-isothiocyanatobenzoate → HCID 178463791, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-isothiocyanatobenzoate | HCID 137833 | — |
| Reactant | HCID 68443017 | HCID 68443017 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | HCID 178463791 | HCID 178463791 | — |
Reaction Steps
4,5-Diamino-N-benzothiazol-6-yl-2-diethylaminobenzamide (0.3 mmol; see Example 133) from above was reacted with 3-isothiocyanatobenzoic acid methyl ester (0.3 mmol) followed by cyclization in situ using EDC as described in general procedure B to obtain 3-[5-(benzothiazol-6-ylcarbamoyl)-6-diethylamino-1H-benzoimidazol-2-ylamino]-benzoic acid methyl ester. MS: m/z 515 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820821B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-73af5bd37d4c475b8ad58daed7ed7277 |
| Source note | uspto-grants-2010_10 |