HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 1,3-Dihydro-4-(1-oxobutyl)-2H-imidazol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Butyryl chloride | HCID 8855 | — |
| Reactant | 2-Hydroxyimidazole | HCID 22208 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1,3-Dihydro-4-(1-oxobutyl)-2H-imidazol-2-one | HCID 13072006 | — |
Reaction Steps
In 10 ml of dichloromethane is placed 1.0 g of 1,3-dihydro-2H-imidazol-2-one, 1.28 g of butyryl chloride and 4.8 g of aluminum chloride. The mixture is refluxed and stirred for 2 hours after which it is poured into water. The precipitate is collected, washed with water, and recrystallized from ethanol:water, to give the title compound, m.p. 268°-270° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04367236 |
| Source dataset | uspto-grants-1983_01 |
| ORD ID | ord-bcf013527d5e40699b0938753624899e |
| Source note | uspto-grants-1983_01 |