HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 23037982, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | Benzamide, N-[4,5-dihydro-5-oxo-1-(2,4,6-trichlorophenyl)-1H-pyrazol-3-yl]-3-nitro- | HCID 113055 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 23037982 | HCID 23037982 | 96.6% |
Reaction Steps
428 g (1.0 mol) of 1-(2,4,6-trichlorophenyl)-3-(3-nitrobenzamido)-5-oxo-2-pyrazoline was added to 2.2 liters of dimethylformamide. To the solution, there was added dropwise 160 g (1.0 mol) of bromine with stirring while cooling with ice, and after stirring for about 1 hour, the reaction solution was poured into 9 liters of water. The crystals thus-separated were collected by filtration to obtain 489.5 g (96.6% yield) of 1-(2,4,6-trichlorophenyl)-3-(3-nitrobenzamido)-4-bromo-5-oxo-2-pyrazoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04367282 |
| Source dataset | uspto-grants-1983_01 |
| ORD ID | ord-3c1c8b76df9b466ca372bba73f687fd3 |
| Source note | uspto-grants-1983_01 |