反应详情

54.5 g (0.17 mol) of 1-(2,4,6-trichlorophenyl)-3-acetylamino-5-oxo-2-pyrazoline was dissolved in 300 ml of acetic acid, to which there was then gradually added dropwise 27.2 g (0.17 mol) of bromine. After stirring for 1 hour, the reaction mixture was poured into 900 ml of water and the crystals thus-separated were collected by filtration to obtain 57 g (84% yield) of 1-(2,4,6-trichlorophenyl)-3-acetylamino-4-bromo-5-oxo-2-pyrazoline.

1. customthe crystals thus-separated
2. filtrationwere collected by filtration