Acetic Anhydride → HCID 20513482, compound

HRID 1163998Notes

Reaction equation

HRID 1163998 reaction equation
[Cl:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][CH:8]=[C:9]([CH3:12])[C:10]=1[OH:11].[C:17](OC(=O)C)(=[O:19])[CH3:18]>C(O)(=O)C>[C:17]([O:11][C:10]1[C:9]([CH3:12])=[CH:8][CH:7]=[CH:6][C:5]=1[O:4][C:3]1[CH:13]=[CH:14][CH:15]=[CH:16][C:2]=1[Cl:1])(=[O:19])[CH3:18]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 20513480HCID 20513480, compound

Product 1

HCID 20513482HCID 20513482, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of 6-(2-chlorophenoxy)-o-cresol (0.3 g), acetic acid (5 ml) and acetic anhydride (5 ml) was refluxed under heating for 7 hours. The reaction mixture was evaporated, and the oily residue was dissolved in diethyl ether, washed with an aqueous solution of sodium bicarbonate, dried over magnesium sulfate and then evaporated to give oily 2-chlorophenyl 2-acetoxy-3-methylphenyl ether (0.4 g).

Workup

  1. temperaturewas refluxed
  2. temperatureunder heating for 7 hours
  3. customThe reaction mixture was evaporated
  4. dissolutionthe oily residue was dissolved in diethyl ether
  5. washwashed with an aqueous solution of sodium bicarbonate
  6. dry with materialdried over magnesium sulfate
  7. customevaporated

Sources & evidence

ORD record
ord-5d8ce92e24154446813626c24f9c3da0
Source dataset
uspto-grants-1983_01
Patent number
US04367238

Reaction notes

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