HCID 13066682, compound → HCID 20513423, compound

HRID 1164008Notes

Reaction equation

HRID 1164008 reaction equation
O[C:2]1[C:7]([O:8][C:9]2[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][CH:10]=2)=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:16][C:17]([OH:19])=[O:18]>C(OC(=O)C)(=O)C>[Cl:15][C:12]1[CH:11]=[CH:10][C:9]([O:8][C:7]2[C:2]3[O:19][C:17](=[O:18])[CH2:16][C:3]=3[CH:4]=[CH:5][CH:6]=2)=[CH:14][CH:13]=1

Participants

3

Reactant 1

HCID 13066682HCID 13066682, compound

Product 1

HCID 20513423HCID 20513423, compound

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

2-[2-Hydroxy-3-(4-chlorophenoxy)phenyl]acetic acid (2 g) was dissolved in acetic anhydride (10 ml) under warming, and the reaction mixture was evaporated. The resultant crystals were recrystallized from an aqueous ethanol to give 7-(4-chlorophenoxy)-2,3-dihydrobenzofuran-2-one, mp 100°-102° C.

Workup

  1. temperatureunder warming
  2. customthe reaction mixture was evaporated
  3. customThe resultant crystals were recrystallized from an aqueous ethanol

Sources & evidence

ORD record
ord-d483c8afaccc41479a31e25cffb17b9c
Source dataset
uspto-grants-1983_01
Patent number
US04367238

Reaction notes

Loading…