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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1164012Generated: November 1, 2026

Sodium Cyanide → 2-[2-Methoxy-3-(3-chlorophenoxy)phenyl]acetonitrile

https://huagongshe.com/reaction/1164012

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium CyanideHCID 8929—
ReactantHCID 20513502HCID 20513502—
SolventDimethyl SulfoxideHCID 679—
Product2-[2-Methoxy-3-(3-chlorophenoxy)phenyl]acetonitrileHCID 2051349098.1%

Reaction Steps

A solution of 3-chlorophenyl 2-methoxy-3-bromomethylphenyl ether (20 g) in dimethyl sulfoxide (50 ml) and powdered sodium cyanide (3 g) were treated in a similar manner to that of Example 5-(4) to give oily 2-[2-methoxy-3-(3-chlorophenoxy)phenyl]acetonitrile (16.4 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04367238
Source datasetuspto-grants-1983_01
ORD IDord-4be2251b8bac417594227322f45d4e5c
Source noteuspto-grants-1983_01