Water → HCID 20513503, compound

HRID 1164059Notes

Reaction equation

HRID 1164059 reaction equation
[CH3:1][O:2][C:3]1[C:8]([O:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:16][C:17]#N.[OH-:19].[K+].[OH2:21]>C(O)C>[CH3:1][O:2][C:3]1[C:8]([O:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:16][C:17]([OH:21])=[O:19]

Participants

5

Reactant 3

HCID 962WaterHCID 14797Potassium HydroxideHCID 20513452HCID 20513452, compound

Product 1

HCID 20513503HCID 20513503, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 2-(2-methoxy-3-phenoxyphenyl)acetonitrile (2.5 g) and potassium hydroxide (2.3 g) in water (20 ml) and ethanol (40 ml) was treated in a similar manner to that of Example 17-(1) to give oily 2-(2-methoxy-3-phenoxyphenyl)acetic acid (2.1 g).

Workup

  1. additionwas treated in a similar manner to that of Example 17-(1)

Sources & evidence

ORD record
ord-5991a5129f2c436a9abfac9096fe9b19
Source dataset
uspto-grants-1983_01
Patent number
US04367238

Reaction notes

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