反应详情

温度

110 °C

A mixture of 2-(o-tolylthio)-6-allylphenol (24 g) and potassium hydroxide (32 g) in methanol (100 ml) was stirred at 110° C. Methanol was distilled off from the mixture under ordinal pressure, and the mixture was stirred at 100° C. for an hour. The reaction mixture was cooled, acidified with conc. hydrochloric acid and extracted with diethyl ether. The extract was washed with water, dried and evaporated under reduced pressure to give oily 2-(o-tolylthio)-6-(1-propenyl)phenol (24.3 g).

1. distillationMethanol was distilled off from the mixture under ordinal pressure
2. stirringthe mixture was stirred at 100° C. for an hour
3. temperatureThe reaction mixture was cooled
4. extractionextracted with diethyl ether
5. washThe extract was washed with water
6. customdried
7. customevaporated under reduced pressure