HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 2-cyano-2-[2-methoxy-3-(o-tolylthio)phenyl]acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | 2-[2-Methoxy-3-(o-tolylthio)phenyl]acetonitrile | HCID 20513450 | — |
| Reactant | CID 21226545 | HCID 21226545 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Ethyl 2-cyano-2-[2-methoxy-3-(o-tolylthio)phenyl]acetate | HCID 20513407 | 96.3% |
Reaction Steps
Sodium metal (0.7 g), dried ethanol (20 ml), 2-[2-methoxy-3-(o-tolylthio)phenyl]acetonitrile (7.7 g), ethyl carbonate (13 g) and toluene (50 ml) were treated in a similar manner to that of Example 22-(1) to give oily ethyl 2-cyano-2-[2-methoxy-3-(o-tolylthio)phenyl]acetate (9.4 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04367238 |
| Source dataset | uspto-grants-1983_01 |
| ORD ID | ord-7bce8b8e7142496caed216b2247f7946 |
| Source note | uspto-grants-1983_01 |