3-Hydroxyisobenzofuran-1(3H)-one → (13E)-(6RS,9alpha,11alpha,15S)-6,9-Epithio-11,15-dihydroxyprost-13-enoic acid 2-hydroxyethyl ester

HRID 1164159Notes

Reaction equation

HRID 1164159 reaction equation
C1(C2[C:5](=CC=CC=2)[CH:4]([O:11][C:12](=[O:35])[CH2:13][CH2:14][CH2:15][CH2:16][CH:17]2[S:34][C@H:20]3[CH2:21][C@@H:22]([OH:33])[C@H:23](/[CH:24]=[CH:25]/[C@@H:26]([OH:32])[CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])[C@H:19]3[CH2:18]2)O1)=O.[OH:36]C1C2C(=CC=CC=2)C(=O)O1>>[OH:36][CH2:5][CH2:4][O:11][C:12](=[O:35])[CH2:13][CH2:14][CH2:15][CH2:16][CH:17]1[S:34][C@H:20]2[CH2:21][C@@H:22]([OH:33])[C@H:23](/[CH:24]=[CH:25]/[C@@H:26]([OH:32])[CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])[C@H:19]2[CH2:18]1

Participants

3

Reactant 2

HCID 38042593-Hydroxyisobenzofuran-1(3H)-oneHCID 86738736(13E)-(6RS,9alpha,11alpha,15S)-6,9-Epithio-11,15-dihydroxyprost-13-enoic acid phthalid-3-yl ester

Product 1

HCID 86738735(13E)-(6RS,9alpha,11alpha,15S)-6,9-Epithio-11,15-dihydroxyprost-13-enoic acid 2-hydroxyethyl ester

Procedure

(13E)-(6RS,9α,11α,15S)-6,9-Epithio-11,15-dihydroxyprost-13-enoic acid phthalid-3-yl ester from 3-hydroxyphthalide.

Sources & evidence

ORD record
ord-826b2112723940beae7460bfb47ba740
Source dataset
uspto-grants-1983_01
Patent number
US04367237

Reaction notes

Loading…