Pyridine → {4-[1-(Biphenyl-2-carbonyl)-1H-pyrazol-3-yl]-phenyl}-(5H,11H-pyrrolo[2,1-c][1,4]benzodiazepin-10-yl)-methanone

HRID 116417Notes

Reaction equation

HRID 116417 reaction equation
[c:28]1(-[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[c:29]([C:34](=[O:35])[Cl:36])[cH:30][cH:31][cH:32][cH:33]1.[cH:43]1[cH:44][cH:45][n:46][cH:47][cH:48]1.[nH:1]1[n:2][c:3](-[c:6]2[cH:7][cH:8][c:9]([C:12](=[O:13])[N:14]3[CH2:15][c:16]4[n:17]([cH:25][cH:26][cH:27]4)[CH2:18][c:19]4[c:20]3[cH:21][cH:22][cH:23][cH:24]4)[cH:10][cH:11]2)[cH:4][cH:5]1>>[n:1]1([C:34]([c:29]2[c:28](-[c:37]3[cH:38][cH:39][cH:40][cH:41][cH:42]3)[cH:33][cH:32][cH:31][cH:30]2)=[O:35])[n:2][c:3](-[c:6]2[cH:7][cH:8][c:9]([C:12](=[O:13])[N:14]3[CH2:15][c:16]4[n:17]([cH:25][cH:26][cH:27]4)[CH2:18][c:19]4[c:20]3[cH:21][cH:22][cH:23][cH:24]4)[cH:10][cH:11]2)[cH:4][cH:5]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 12563768[1,1'-Biphenyl]-2-carbonyl chlorideHCID 178519422HCID 178519422, compound

Product 1

HCID 9850040{4-[1-(Biphenyl-2-carbonyl)-1H-pyrazol-3-yl]-phenyl}-(5H,11H-pyrrolo[2,1-c][1,4]benzodiazepin-10-yl)-methanone

Sources & evidence

ORD record
ord-011fde7e3b5e43d1a5d0fb90de94025e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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