反应详情

温度

20 °C

The procedure of Example 1 was repeated except that the organic phase containing p-hydroxymandelic acid was treated with a molar equivalent of sodium hydroxide as a 50% w/w aqueous solution. The caustic solution was added over one hour during which time the methyl isobutyl ketone solution was maintained at about 20° C. with cooling. The precipitate of sodium p-hydroxymandelate monohydrate was filtered off and suctioned as dry as possible before drying under vacuum at 40° C.

1. temperaturewith cooling
2. filtrationThe precipitate of sodium p-hydroxymandelate monohydrate was filtered off
3. customas dry as possible
4. custombefore drying under vacuum at 40° C.