Phosphoric Acid → Maltol

HRID 1164274Notes

Reaction equation

HRID 1164274 reaction equation
Br[C:2]1[C:3](=[O:10])[CH:4]([CH3:9])[O:5][CH:6](O)[CH:7]=1.P(=O)(O)(O)[OH:12]>>[CH3:9][C:4]1[O:5][CH:6]=[CH:7][C:2](=[O:12])[C:3]=1[OH:10]

Participants

3

Reactant 2

HCID 1004Phosphoric AcidHCID 204685984-Bromo-6-hydroxy-2-methyl-2H-pyran-3(6H)-one

Product 1

HCID 8369MaltolYield 34%

Procedure

A solution of 4-bromo-6-hydroxy-2-methyl-2H-pyran-3(6H)-one (0.0025 mole) in 20 ml of 35% phosphoric acid was refluxed for about 5 hours. Maltol (34%) was isolated by the method of Example 1.

Sources & evidence

ORD record
ord-cd922887681645e581e8d095994c8ffd
Source dataset
uspto-grants-1983_01
Patent number
US04368331

Reaction notes

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