HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diazomethane → Aniracetam
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diazomethane | HCID 9550 | — |
| Reactant | HCID 12726273 | HCID 12726273 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Aniracetam | HCID 2196 | — |
Reaction Steps
150 mg. of 1-(p-hydroxybenzoyl)-2-pyrrolidinone are dissolved in 7 ml. of absolute tetrahydrofuran and then etheric diazomethane solution is added. The solvents are distilled off, the residue is triturated with diethyl ether and the mixture is filtered. There is obtained 1-(p-methoxybenzoyl)-2-pyrrolidinone which melts at 117.5°-119° C. after sublimation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04369139 |
| Source dataset | uspto-grants-1983_01 |
| ORD ID | ord-94825f96346a4b0e8fdbc8471c5569a5 |
| Source note | uspto-grants-1983_01 |