HCID 86738751, compound → Vincamine

HRID 1164315Notes

Reaction equation

HRID 1164315 reaction equation
[CH3:1][CH2:2][C@:3]12[CH2:19][C@:18]([OH:24])([C:20]([O:22][CH3:23])=[O:21])[N:17]3[C:9]4=[C:10]([CH2:25][CH2:26][N:7]([C@@H:8]14)[CH2:6][CH2:5][CH2:4]2)[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:16]=13.CS([O-])(=O)=O>O>[CH3:1][CH2:2][C@:3]12[CH2:19][C@:18]([OH:24])([C:20]([O:22][CH3:23])=[O:21])[N:17]3[C:9]4=[C:10]([CH2:25][CH2:26][N:7]([C@@H:8]14)[CH2:6][CH2:5][CH2:4]2)[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:16]=13

Participants

3

Reactant 1

HCID 86738751HCID 86738751, compound

Product 1

HCID 15376VincamineYield 462.9%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

100 g of vincamine methanesulfonate are dissolved in 1 liter of deionised water. Then 365 g of the activated resin obtained in accordance with the above particulars are slowly dispersed in this solution. The mixture is then stirred at 40° C. until all the active ingredient is bound on the resin. The residual concentration of the vincamine salt in the solution is kept under observation by UV spctrophotometry. The vincamine resinate is collected by filtration and dried to constant weight in vacuo at 50° C.

Sources & evidence

ORD record
ord-a9038be04d57421aadd6fa6703f77017
Source dataset
uspto-grants-1983_01
Patent number
US04369175

Reaction notes

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