HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Nitro-benzothiazol-2-yl-carbamic acid ethyl ester → 2-Amino-6-nitrobenzothiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Nitro-benzothiazol-2-yl-carbamic acid ethyl ester | HCID 331997 | — |
| Reactant | ethyl N-(1,3-benzothiazol-2-yl)carbamate | HCID 854169 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Amino-6-nitrobenzothiazole | HCID 22704 | — |
Reaction Steps
19 g (0.09 mol) of benzothiazol-2-yl-carbamic acid ethyl ester are nitrated as described in Example 1. The resulting water-moist paste of 6-nitro-benzothiazol-2-yl-carbamic acid ethyl ester is saponified at pH 10 to 12 and the mixture is worked up, as described in Example 1. 9.8 g of 2-amino-6-nitrobenzothiazole of melting point 249° to 252° C. are obtained. The content of isomeric nitro compounds is less than 1%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04369324 |
| Source dataset | uspto-grants-1983_01 |
| ORD ID | ord-d7172455e8b94f63b221577701da8931 |
| Source note | uspto-grants-1983_01 |